A new study published in JACC Advances on March 18, 2025, reveals that marijuana users face a significantly higher risk of life-threatening heart conditions, including heart attacks and strokes, compared to non-users. The research found that adults under 50 who use marijuana are more than six times as likely to suffer a heart attack and face an elevated risk of stroke, heart failure, and cardiovascular-related death.
Lead researcher Dr. Ibrahim Kamel of Boston University emphasized the need for doctors to inquire about cannabis use during routine check-ups, similar to how they assess smoking habits.
The study, which analyzed data from over 75 million people across the US, Canada, and India, focused on individuals with no prior heart conditions or risk factors such as high blood pressure, diabetes, or smoking. Findings showed that marijuana users had a sixfold increase in heart attack risk, were twice as likely to develop heart failure, and had a fourfold higher chance of experiencing an ischemic stroke.
While the study highlights the dangers of cannabis use, Dr. Kamel cautioned that limitations exist, including the lack of data on usage frequency and potential interactions with other substances. Despite marijuana’s well-known medicinal benefits, concerns about its long-term effects continue to grow, with previous research also linking cannabis to mental health issues, cognitive impairment, and addiction.
Kamel and his team suggest that cannabis may impact heart rhythm, increase oxygen demand in the heart, and contribute to poor blood flow regulation. With marijuana use becoming more widespread, researchers stress the importance of further studies to fully understand its impact on cardiovascular health.